Presenter(s)

    Lauren Alexis Carothers

    Comments

    Presentation: 10:45-12:00, Kennedy Union Ballroom

    Download

    Download Project (1.2 MB)

    Description

    Electrospun nanofibers are extensively studied materials in tissue engineering for both in vivo and in vitro applications. Despite their potential, the delicate and friable nature of nanofibers poses challenges in handling and utilizing them for cell culture substrates. To address this, we investigated the feasibility of 3D printing circular frames using a UV curable resin onto chitosan nanofiber mats Our aim was to evaluate the adhesion and proliferation of cultured cells on variously positioned nanofibers, including rings and coins, and orientations both upwards and downwards, to assess their biocompatibility over time. To evaluate the confluency and proliferation, we utilized a combination of tests including CCK8, GFP imaging, and JMP software analysis.

    Publication Date

    4-17-2024

    Project Designation

    Independent Research

    Primary Advisor

    Russell K. Pirlo

    Primary Advisor's Department

    Chemical and Materials Engineering

    Keywords

    Stander Symposium, School of Engineering

    Institutional Learning Goals

    Scholarship

    Research on the Biocompatibility of Nanofibers for Microneedles

    Share

    COinS