Presenter(s)

Lauren Alexis Carothers

Comments

Presentation: 10:45-12:00, Kennedy Union Ballroom

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Description

Electrospun nanofibers are extensively studied materials in tissue engineering for both in vivo and in vitro applications. Despite their potential, the delicate and friable nature of nanofibers poses challenges in handling and utilizing them for cell culture substrates. To address this, we investigated the feasibility of 3D printing circular frames using a UV curable resin onto chitosan nanofiber mats Our aim was to evaluate the adhesion and proliferation of cultured cells on variously positioned nanofibers, including rings and coins, and orientations both upwards and downwards, to assess their biocompatibility over time. To evaluate the confluency and proliferation, we utilized a combination of tests including CCK8, GFP imaging, and JMP software analysis.

Publication Date

4-17-2024

Project Designation

Independent Research

Primary Advisor

Russell K. Pirlo

Primary Advisor's Department

Chemical and Materials Engineering

Keywords

Stander Symposium, School of Engineering

Institutional Learning Goals

Scholarship

Research on the Biocompatibility of Nanofibers for Microneedles

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