AMR research | Antimicrobial Resistance: Research, Resources, and Commentary | University of Dayton
 
This collection contains research in antimicrobial resistance by Fred C. Tenover and other researchers. In almost all cases, a version of the research is available open-access.

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Submissions from 2024

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A Teleological View of Novel Molecular Diagnostics: Identifications vs Probabilities, Fred Tenover

Submissions from 2023

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Challenges in Forecasting Antimicrobial Resistance, Sen Pei, Seth Blumberg, Jaime Cascante Vega, Tal Robin, Yue Zhang, Richard J. Medford, Bijaya Adhikari, and Jeffrey Shaman

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Directed Carbapenemase Testing Is No Longer Just for Enterobacterales: Cost, Labor, and Workflow Assessment of Expanding Carbapenemase Testing to Carbapenem-Resistant P. aeruginosa, Fred C. Tenover, Christian M. Gill, Poonam Rajkotia, Amity L. Roberts, and David P. Nicolau

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Surveillance and Stewardship: Where Infection Prevention and Antimicrobial Stewardship Intersect, Fred C. Tenover and Debra A. Goff

Submissions from 2022

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The antimicrobial resistance crisis needs action now, Nonia Pariente

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Clinical Performance of the Xpert® CT/NG Test for Detection of Chlamydia trachomatis and Neisseria gonorrhoeae: A Multicenter Evaluation in Chinese Urban Hospitals, Fred C. Tenover, Yan Han, Mei-Qin Shi, Qing-Ping Jiang, Wen-Jing Le, Xiao-Lin Qin, Han-Zhen Xiong, He-Ping Zheng, Yi-Wei Tang, and Yue-Ping Yin

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Carbapenemase-Producing Pseudomonas aeruginosa – an Emerging Challenge, Fred C. Tenover, David P. Nicolau, and Christian M. Gill

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Detection of Methicillin-Resistant Staphylococcus aureus Infections Using Molecular Methods, Fred C. Tenover and Isabella A. Tickler

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A Pooling Strategy for Detecting Carbapenem Resistance Genes by the Xpert Carba-R Test in Rectal Swab Specimens, Fred C. Tenover, Peng Zhang, Qi Wang, Chaoe Zhou, Feifei Zhang, Xinghui Gao, Yi-Wei Tang, and Hui Wang

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Characterization of SCCmec Instability in Methicillin-Resistant Staphylococcus aureus Affecting Adjacent Chromosomal Regions, Including the Gene for Staphylococcal Protein A (spa), Isabella A. Tickler, Fred C. Tenover, C. R. Scharn, and R. V. Goering

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Mechanisms of Carbapenemase-Mediated Resistance among High-Risk Pseudomonas aeruginosa Lineages in Peru, Isabella A. Tickler, Juan Carlos Gomez De La Torre, Luis Alvarado, Anne E. Obradovich, and Fred C. Tenover

Submissions from 2021

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Threats of antibiotic resistance: An obliged reappraisal, Fernando Baquero

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Antimicrobial resistance: A challenge awaiting the post-COVID-19 era, Tekle Airgecho Lobie, Aklilu Abrham Roba, James Alexander Booth, Knut Ivan Kristiansen, Abraham Aseffa, Kirsten Skarstad, and Magnar Bjørås

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Using Molecular Diagnostics to Develop Therapeutic Strategies for Carbapenem-Resistant Gram-Negative Infections, Fred C. Tenover

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Molecular Detection of Carbapenem Resistance Genes in Rectal Swabs from Patients in Gulf Cooperation Council Hospitals, Fred C. Tenover, Manaf AlQahtani, Isabella A. Tickler, Z. Al Deesi, W. AlFouzan, A. Al Jabri, R. Al Jindan, S. Al Johani, S. A. Alkahtani, A. Al Kharusi, E. Mokaddas, A. Nabi, N. Saeed, A. Madian, and J. Whitmore

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Phenotypic/Genotypic Profile of Oxa-10-like-Harboring, Carbapenem-Resistant Pseudomonas aeruginosa: Using Validated Pharmacokinetic/Pharmacodynamic in Vivo Models to Further Evaluate Enzyme Functionality and Clinical Implications, Fred C. Tenover, Christian M. Gill, Adrian Brink, Chun Yat Chu, Jennifer Coetzee, George Dimopoulos, Clinton Moodley, Christoffel Johannes Opperman, Spyros Pournaras, Isabella A. Tickler, Hafsah Deepa Tootla, Sophia Vourli, and David P. Nicolau

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Parallel Validation of the Ng-Test Carba 5 and the Xpert Carba-R for Detection and Characterization of Carbapenem-Resistant Enterobacterales Causing Bloodstream Infections, Fred C. Tenover, Zeshi Liu, Lu Bai, Jiayun Liu, Jing Lei, Xinghui Gao, Ke Lei, Yi-Wei Tang, Yan Geng, and Aili He

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Characterization of Carbapenem-Resistant Gram-Negative Bacterial Isolates from Nigeria by Whole Genome Sequencing, Isabella A. Tickler BS, Fred C. Tenover PhD, Caitlin M. dela Cruz BS, Shuwaram A. Shettima MBBS, Victoria M. Le BS, Scott Dewell PhD, and Jack Sumner BS

Submissions from 2020

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Characterisation of carbapenem-resistant Gram-negative organisms from clinical specimens in Yola, Nigeria, Shuwaram A. Shettima, Isabella A. Tickler, Caitlin M. dela Cruz, and Fred C. Tenover

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Does the Presence of Multiple β-Lactamases in Gram-Negative Bacilli Impact the Results of Antimicrobial Susceptibility Tests and Extended-Spectrum β-Lactamase and Carbapenemase Confirmation Methods?, Fred C. Tenover, Caitlin M. dela Cruz, Scott Dewell, Victoria M. Le, and Isabella A. Tickler

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Does the presence of multiple β-lactamases in Gram-negative bacilli impact the results of antimicrobial susceptibility tests and extended-spectrum β-lactamase and carbapenemase confirmation methods?, Fred C. Tenover, Caitlin M. dela Cruz, Scott Dewell, Victoria M. Le, and Isabella A. Tickler

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Evaluation of the Xpert Carba-R Nxg Assay for Detection of Carbapenemase Genes in a Global Challenge Set of Pseudomonas aeruginosa Isolates, Fred C. Tenover, Christian M. Gill, Tomefa E. Asempa, Isabella A. Tickler, Caitlin M. dela Cruz, and David P. Nicolau

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Multicenter Evaluation of Xpert Carba-R Assay for Detection and Identification of the Carbapenemase Genes in Rectal Swabs and Clinical Isolates, Fred C. Tenover, Xi Jin, Haomin Zhang, Shi Wu, Xiaohua Qin, Peiyao Jia, Yi-Wei Tang, Min Li, Fupin Hu, Qiwen Yang, and Yunsong Yu

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Presence of Clostridioides difficile and multidrug-resistant healthcare-associated pathogens in stool specimens from hospitalized patients in the USA, Isabella A. Tickler, Caitlin M. dela Cruz, Anne E. Obradovich, Richard V. Goering, Scott Dewell, Victoria M. Le, Fred C. Tenover, and Healthcare Associated Infections Consortium

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Mobile genetic elements responsible for discordant Staphylococcus aureus phenotypes and genotypes in the same blood culture bottle, Isabella A. Tickler, Richard V. Goering, Scott Dewell, Victoria M. Le, Leepakshi Johar, Anne E. Obradovich, and Fred C. Tenover

Submissions from 2019

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Emergence of Oxacillin Resistance in Stealth Methicillin-Resistant Staphylococcus aureus Due to mecA Sequence Instability, Richard V. Goering, Erin A. Swartzendriber, Anne E. Obradovich, Isabella A. Tickler, and Fred C. Tenover

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Diversity of resistance mechanisms in carbapenem-resistant Enterobacteriaceae at a health care system in Northern California, from 2013 to 2016, Fiona Senchyna, Rajiv L. Gaur, Johanna Sandlund, Cynthia Truong, Guillaume Tremintin, Dietmar Kültz, Carlos A. Gomez, Fiona B. Tamburini, Tessa Andermann, Ami Bhatt, Isabella A. Tickler, Nancy Watz, Indre Budvytiene, Gongyi Shi, Fred C. Tenover, and Niaz Banaei

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Updating Molecular Diagnostics for Detecting Methicillin- Susceptible and Methicillin-Resistant Staphylococcus aureus Isolates in Blood Culture Bottles, Fred C. Tenover, Isabella A. Tickler, Victoria M. Le, Scott Dewell, Rodrigo E. Mendes, Richard V. Goering, and MRSA Consortium

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Changes in molecular epidemiology and antimicrobial resistance profiles of Clostridioides (Clostridium) difficile strains in the United States between 2011 and 2017, Isabella A. Tickler, Anne E. Obradovich, Richard V. Goering, Ferric C. Fang, Fred C. Tenover, and HAI Consortium

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Streptococcus agalactiae Strains with Chromosomal Deletions Evade Detection with Molecular Methods, Isabella A. Tickler, Fred C. Tenover, Scott Dewell, Victoria M. Le, Rachel N. Blackman, Richard V. Goering, Amy E. Rogers, Heather Piwonka, Brittney D. Jung-Hynes, Derrick J. Chen, Michael J. Loeffelholz, Devasena Gnanashanmugam, and Ellen Jo Baron

Submissions from 2018

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Direct Detection of Mycobacterium tuberculosis in Clinical Specimens Using Nucleic Acid Amplification Tests, Ellen Jo Baron, Fred C. Tenover, and Devasena Gnanashanmugam

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Range Expansion and the Origin of USA300 North American Epidemic Methicillin-Resistant Staphylococcus aureus, Lavanya Challagundla, Isabella A. Tickler, Xavier Didelot (0000-0003-1885-500X), David C. Coleman (0000-0003-1797-2888), Anna C. Shore (0000-0002-6667-0918), Geoffrey W. Coombs, Daniel O. Sordelli, Eric L. Brown, Robert Skov, Anders Rhod Larsen, Jinnethe Reyes, Iraida E. Robledo, Guillermo J. Vazquez, Paul Rivera, Paul D. Fey, Kurt Stevenson, Shu-Hua Wang, Barry N. Kreiswirth, Jose R. Mediavilla, Cesar A. Arias, Paul J. Planet, Rathel L. Nolan, Fred C. Tenover, Richard V. Goering, and D. Ashley Robinson

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Prospective study of the feasibility of point-of-care testing strategy for carbapenem-resistant organism detection, Rahul Pannala, Bruce Baldwin, Vijay Aluru, Thomas E. Grys, Jordan Holmes, Laurence J. Miller, M. Edwyn Harrison, Cuong C. Nguyen, Fred C. Tenover, David Persing, and Douglas O. Faigel

Laboratory diagnosis of Clostridium difficile infection, Fred C. Tenover

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The role for rapid molecular diagnostic tests for infectious diseases in precision medicine, Fred C. Tenover

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Strain types of Staphylococcus aureus nasal isolates from persons undergoing joint replacement surgery, Fred C. Tenover, Kebert Eloi, Isabella A. Tickler, Susan Cohen, Gary B. Schneider, and Steven C. Vlad

Submissions from 2017

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Continued expansion of USA300-like methicillin-resistant Staphylococcus aureus (MRSA) among hospitalized patients in the United States, Isabella A. Tickler, Richard V. Goering, Jose R. Mediavilla, Barry N. Kreiswirth, and Fred C. Tenover

Submissions from 2016

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Antibiotic use and its consequences for the normal microbiome, Martin J. Blaser

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Screening of nursing home residents for colonization with carbapenem-resistant Enterobacteriaceae admitted to acute care hospitals: Incidence and risk factors, Cheston B. Cunha, Steven Z. Kassakian, Ryan Chan, Fred C. Tenover, Panos Ziakas, Kimberle C. Chapin, and Leonard A. Mermel

Submissions from 2015

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Antimicrobial resistance: a global multifaceted phenomenon, Francesca Prestinaci, Patrizio Pezzotti, and Annalisa Pantosti

Submissions from 2011

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Laboratory Diagnosis of Clostridium difficile Infection: Can Molecular Amplification Methods Move Us Out of Uncertainty?, Fred C. Tenover, Ellen Jo Baron, Lance R. Peterson, and David Persing